simulation-architect
Design and implementation of comprehensive simulation studies
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Design and implementation of comprehensive simulation studies
Provides guidance for training and analyzing Sparse Autoencoders (SAEs) using SAELens to decompose neural network activations into interpretable features. Use when discovering interpretable features, …
Systematic reviews of complex interventions per Cochrane Handbook Ch 17. Use when the intervention has multiple interacting components, is context-dependent, or involves behaviour change. Logic models…
Systematic review Phase 8 — GRADE assessment and Summary of Findings for EM/critical care SRs. Use when the user needs to rate certainty of evidence, generate a Summary of Findings (SoF) table, apply …
Handle patient-reported outcomes (PROs) in systematic reviews per Cochrane Handbook Ch 18. Use when included studies use patient-reported outcomes like quality of life, pain, function, or symptom scal…
Systematic review Phase 2 — Protocol writing and PROSPERO registration for EM/critical care SRs. Use when the user needs a full PRISMA-P-compliant protocol, PROSPERO field mapping, timeline estimation…
Systematic review Phase 3 — Literature search, string construction, database translation, deduplication, and PRISMA-S compliance for EM/critical care SRs. Use when the user needs to build, test, or re…
Systematic review Phase 9 — PRISMA 2020 compliant manuscript writing for EM/critical care SRs with journal-specific formatting. Use when the user needs to write the full manuscript, any section (abstr…
Multi-cloud orchestration for ML workloads with automatic cost optimization. Use when you need to run training or batch jobs across multiple clouds, leverage spot instances with auto-recovery, or opti…
Systematic review of adverse effects per Cochrane Handbook Ch 19. Use when the review includes harm outcomes, rare events, zero-event studies, or safety-focused synthesis. Includes different study des…
Integrate economic evidence into SRs per Cochrane Handbook Ch 20 + 20.S. Use when the review includes cost-effectiveness, cost-utility, or cost-benefit analyses. CHEERS 2022 compliance, CHEC-list crit…
Structured interpretation of SR results per Cochrane Handbook Ch 15. Use when the user needs to interpret meta-analysis results, compute NNT, re-express SMDs, assess applicability, or draw conclusions…
Systematic review Phase 1 — PICO development and topic formulation for EM/critical care. Use when the user wants to define their research question, build a PICO(S) framework, identify eligibility crit…
Handle non-standard RCT designs in SRs per Cochrane Handbook Ch 23. Use when included studies include cluster RCTs, crossover trials, stepped-wedge designs, equivalence/non-inferiority trials, or mult…
Systematic review Phase 7 — Statistical synthesis, meta-analysis, and heterogeneity assessment for EM/critical care SRs with live R code execution. Use when the user needs to pool data, calculate effe…
Quality assurance and testing protocols for statistical software
Provides guidance for LLM post-training with RL using slime, a Megatron+SGLang framework. Use when training GLM models, implementing custom data generation workflows, or needing tight Megatron-LM inte…
Phase 0 — Topic brainstorming and research gap exploration for EM/critical care SRs. Use when the user has a broad topic area but no specific question yet. Guides through landscape scanning, gap ident…
Systematic review Phase 5 — Data extraction form design, execution, missing data handling, and outcome harmonization for EM/critical care SRs. Use when the user needs an extraction form, help with mis…
Non-meta-analytic synthesis methods per Cochrane Handbook Ch 12. Use when meta-analysis is not possible and alternative synthesis is needed. Three acceptable methods: summarizing effect estimates, com…
Prospective approaches to accumulating evidence per Cochrane Handbook Ch 22. Use when the user needs prospective meta-analysis (PMA), trial sequential analysis (TSA), cumulative meta-analysis, or livi…
Systematic review Phase 6 — Risk of bias assessment using RoB 2.0, ROBINS-I, QUADAS-2, QUIPS, and JBI tools for EM/critical care SRs. Use when the user needs to assess study quality, select the correc…
Systematic review Phase 10 — Living review maintenance, search updates, and new evidence integration for EM/critical care SRs. Use when the user wants to update their review with new evidence, set up …
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